Lots of good information, many "I didn't know that" tips, and great insight into the 'why and how' Lightroom thinks. Two of my key take-aways were 1) in the second Preferences tab named 'Presets', several Restore options are available to use if and when Lightroom acts crazy before you may need to uninstall and reinstall the application. Also, the 'Interface' Tab to me is a tweaking tool that essentially allows you to personalize how you like Lightroom o look for you.
Tips for Setting Up Your Lightroom Preferences provides an overview of most of the Lithroom preferences. While the short 10 minute video Important Lightroom Preferences and Catalog Settings offers a demo of Jeff's instruction.